SMYD5 methylation of rpL40 links ribosomal output to gastric cancer

www.nature.com

SMYD5 methylation of rpL40 links ribosomal output to gastric cancer

www.nature.com

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NatureEnglish · 6 months ago

SMYD5 methylation of rpL40 links ribosomal output to gastric cancer - Nature

www.nature.com

The lysine methyltransferase SMYD5 and its newly identified substrate ribosomal protein L40 are implicated in the progression of gastric adenocarcinoma, and ablation of SMYD5 prevents metastatic disease in mouse models of this cancer.

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